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Improving pig genetic resistance and muscle production through molecular biology

Tuesday, August 19, 2014: 2:30 PM
Bayshore Grand Ballroom B-C (The Westin Bayshore)
Qianqian Kang , State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China
Yiqing Hu , State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China
Yunlong Zou , State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China
Wenping Hu , State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China
Li Li , State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China
Fei Chang , State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China
Yang Li , State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China
Dan Lu , State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China
Zhaolin Sun , State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China
Ran Zhang , State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China
Xiaoxiang Hu , State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China
Qiuyan Li , State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China
Yunping Dai , State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China
Ning Li , State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, China
Recorded Presentation (flv)
Abstract Text:

Genome modification technology of livestock has developed rapidly in recent years. We can not only insert foreign genes or DNA into a specific locus or disrupt an endogenous locus by gene targeting, but it is now possible to precisely engineer the genome. The tools for this include Zinc Finger Nucleases (ZFN), TALENs and most recently CRISPR/Cas9 which are highly efficient. In this brief review, we focus on the current status of gene editing technology as well as molecular biology in farm animals, and their application relevant to improvement of production traits and disease resistance, with emphasis on the pig.

Keywords:

ZFN

TALEN

CRISPR/Cas9

Molecular biology

Livestock animals

See more of: Symposium: Genomics of Disease in Swine
See more of: Species Breeding: Swine
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