GENOME-WIDE ASSOCIATION STUDY FOR MILK-FAT YIELD IN PORTUGUESE HOLSTEIN CATTLE

Abstract Text: A Genome-wide association study was performed to identify quantitative trait loci associated with the EBV of milk-fat yield in Portuguese Holstein cattle. Genotypes of 526 sires were obtained using the Illumina BovineSNP50 BeadChip. Data quality control procedures validated 37,031 SNPs in 29 autosomes. Twelve significant SNPs in association were detected, two (P < 10^‑4) located on BTA3 and the other ten (P < 5 x 10^‑5) SNPs located on BTA3, BTA8, BTA14, BTA17, BTA18 and BTA21. The SNPs ARS-BFGL-NGS-57820 and ARS-BFGL-NGS-4939 on BTA14 were found inside the same haplotype block with DGAT1 gene. The results of the present study confirm the effect of DGAT1 gene on milk-fat yield in Portuguese Holstein cattle.

Keywords:

Dairy cattle

DGAT1 gene

Genome-wide association

Milk-fat yield