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Genome-wide scan for carcass composition as assessed by X-ray computed tomography (CT) in Scottish Blackface lambs

Monday, August 18, 2014: 4:15 PM
Cypress Room (The Westin Bayshore)
Oswald Matika , The Roslin Institute and R(D)SVS, University of Edinburgh, Midlothian, United Kingdom
Marie Anselme-Moizan , INP, Ecole Nationale Vétérinaire, Toulouse, France
Valentina Riggio , The Roslin Institute and R(D)SVS, University of Edinburgh, Midlothian, United Kingdom
Stephen C. Bishop , The Roslin Institute and R(D)SVS, University of Edinburgh, Midlothian, United Kingdom
Recorded Presentation (flv)
Abstract Text: About 600 Blackface lambs born from 2001 to 2003 had their carcass composition assessed using X-ray computed tomography (CT). GWAS was conducted using the Ovine 50k SNP chip on the CT traits that included muscle, fat and bone weights and their proportions as well as muscle and fat densities. Genetic parameter estimates were obtained using both the pedigree and genomic relationship matrix. We obtained moderate to high (0.19-0.78) heritability estimates. GWAS identified some SNPs reaching the genome-wide significance threshold. Both bone weight and bone area had associated SNPs located on ovine chromosome 6 (OAR6) with p-values of 5.55x10-8 and 2.63x10-9, respectively. We also identified a region on OAR6, having an effect on fat. On OAR1, we identified SNPs associated (p= 7.28x10-7) with muscle density. Bone trait SNPs potentially provide an opportunity for fine mapping, and for studying bone growth and malfunction.

Keywords:

Carcass composition

CT traits

GWAS

See more of: Sheep and Goats Breeding (1)
See more of: Species Breeding: Sheep and goats
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