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Genome Regions Associated to Milk Production Traits and Somatic Cell Score in the Mexican Holstein Population
The aim of this study was to identify the genomic markers associated to milk production traits and somatic cell scores of Mexican Holstein cattle. A total of 1,975, 1,602, and 1,595 animals were included in a genome wide association studies (GWAS) for milk yield, milk components, and somatic cell score, respectively. The genotypes included 45,195 SNP. The analyses were performed with a mixed model and regression analysis implemented in GenABEL (R-software). For all traits, a total of 251 markers had statistically significant association (p <0.001) and 69.72% of the SNP were located in genomic regions earlier reported to traits studied in other populations. BTA13 contains 40 SNP with statistically significant association that have not been reported in other studies. These GWAS results confirm the evidence on the well-known genes and identify a suite of new associations in the Mexican Holstein population.
Keywords:
GWAS
Somatic cell scores
Milk production