Genome-wide association studies for growth traits in Colombian Creole cattle using a single-step genomic best linear unbiased prediction (gBLUP)

Abstract Text: We evaluated 3747 animals in a genome-wide association study using the Illumina 50K for growth traits including: birth weight (BWT), weaning weight (WWT) and 16 month weight (16MW) using a single-step gBLUP. We found statistically significant genes associated with BWT, WWT, and 16MW in two regions on the chromosome BTA14 and one region on chromosome BTA6. The genomic regions on chromosome 14 were consistent between traits, and  SNP´s were located on coding region of PKIA and TOX gene and near to HAS2 and PLAG1 genes, this last related to body gain weight and growth in Bos taurus, indicating their potential use in selection to obtain more efficiency in meat production with this breed..

Keywords:

Genome-wide association study

Birth weight

Weaning weight

SNP