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Laminitis-related claw disorders in dairy cattle: A genome-wide association study

Tuesday, August 19, 2014: 5:15 PM
Bayshore Grand Ballroom A (The Westin Bayshore)
Dianne Van der Spek , Animal Breeding and Genomics Centre, Wageningen University, Wageningen, Netherlands
Johan A.M. van Arendonk , Animal Breeding and Genomics Centre, Wageningen University, Wageningen, Netherlands
Henk Bovenhuis , Animal Breeding and Genomics Centre, Wageningen University, Wageningen, Netherlands
Abstract Text:

ABSTRACT: 10 significant and 31 suggestive SNP were identified for laminitis-related claw disorders in a dataset with 1,771 genotyped cows. The SNP were spread across the genome indicating that many SNP, each explaining a small proportion of the genetic variance, influence each claw disorder. Some significant and suggestive SNP were closely located to SNP found in previous research on feet and leg conformation traits. Major genes influencing claw disorders were not identified, but in order to reduce the incidence of claw disorders by breeding, genomic selection is a promising approach.

Keywords:

GWAS

Health

Holstein Friesian

See more of: Integrating the Discovery and Usage of Functional Mutations into Dairy Genomic selection Programs for Complex Traits
See more of: Species Breeding: Dairy cattle
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