Tracking footprints of an experiment of selection in Iberian pigs

Abstract Text: Genomic tools have been used for analyzing the changes originated by an experiment of selection performed on a strain of Iberian pigs. Both pedigree and SNP-based metrics provided similar estimates of the reduction of autosomal genetic diversity (GD) due to selection, equivalent to an 11% of the diversity of a group of contemporary unselected animals with a common demographic history. Different estimates of the loss of GD in SSCX were obtained with both metrics: 10 and 18%, respectively. This may be attributed to the low number of available SNPs. Traces of the performed selection have been identified in regions of chromosomes 1, 3, 4, 15, 17 and X, which include the FAT1-QTL region and some genes related to fatness, as TNC-C and PTGIS. Further gene sequencing and association analysis should be carried out to obtain a better understanding of the causal polymorphisms

Keywords:

Iberian pig

Gene diversity

Selection footprints