Detection Of Pleiotropic QTL Related To Protein Expression And Foie Gras Quality Traits

Abstract Text: The aim is to identify proteomic QTL and their relationships with quality traits in a backcross design optimized for foie gras quality traits detection. Five quality phenotypes and 326 protein spots expression levels were recorded on the fatty livers of 294 mule ducks. Eight QTL and 23 pQTL were identified at least at 5% chromosome wide significance on 2 linkage groups. Eight proteins were identified and were associated with phenotypes to perform multi-trait QTL detections. All the 32 combinations (20 on LG9 and 12 on LG2c) showed a multi-trait QTL at least at 5% chromosome wide significance and 14 out of the 32 combinations showed a pleiotropic QTL. Among them, 9 QTL with a 0.5% chromosome wide significance concerned TPI and ENO1, protein involved in glycolysis. These results suggest the linkage group 2c contains a gene involved in the lipid and/or glucose metabolism.

Keywords: Foie gras; pQTL; Quality