Dynamic and Genetic Signatures of Resistance and Tolerance of pigs to PRRS

Abstract Text:

Using SNP data, we demonstrate that a previously identified QTL conferring resistance of pigs to PRRS does not confer tolerance. Similarly, variation in tolerance cannot be found at sire level. However, by analysing the dynamic relationship between both traits using individual resistance – tolerance trajectories we find significant SNP effects affecting the shape of these trajectories. Evidence of underlying genetic variation suggests it may be possible to target a specific trajectory type, or shift in trajectory, for genetic improvement. This would provide breeders with a means to simultaneously improve resistance and tolerance and their timely interactions.

Keywords:

Tolerance Resistance PRRS