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Using SNP Markers to Estimate Additive, Dominance and Imprinting Genetic Variance

Friday, August 22, 2014: 2:30 PM
Bayshore Grand Ballroom D (The Westin Bayshore)
Marcos S. Lopes , TOPIGS Research Center IPG, Beuningen, Netherlands
John W.M. Bastiaansen , Animal Breeding and Genomics Centre, Wageningen University, Wageningen, Netherlands
Luc Janss , Center for Quantitative Genetics and Genomics, Department of Molecular Biology and Genetics, Aarhus University, Tjele, Denmark
Henk Bovenhuis , Animal Breeding and Genomics Centre, Wageningen University, Wageningen, Netherlands
Egbert F. Knol , TOPIGS Research Center IPG, Beuningen, Netherlands
Abstract Text: The contributions of additive, dominance and imprinting effects to the variance of number of teats (NT) were evaluated in two purebred pig populations using SNP markers. Three different random regression models were evaluated, accounting for the mean and: 1) additive effects (MA), 2) additive and dominance effects (MAD) and 3) additive, dominance and imprinting effects (MADI). Additive heritability estimates were 0.30, 0.28 and 0.27-0.28 in both lines using MA, MAD and MADI, respectively. Dominance heritability ranged from 0.06 to 0.08 using MAD and MADI. Imprinting heritability ranged from 0.01 to 0.02. Dominance effects make an important contribution to the genetic variation of NT in the two lines evaluated. Imprinting effects appeared less important for NT than additive and dominance effects. The SNP random regression model presented and evaluated in this study is a feasible approach to estimate additive, dominance and imprinting variance.

Keywords:

pig

teat number

dominance

imprinting