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Genome-wide association analyses for boar taint components in different Pietrain sired crosses

Thursday, August 21, 2014: 4:00 PM
Bayshore Grand Ballroom B-C (The Westin Bayshore)
Christine Grosse-Brinkhaus , Institute of animal science, University of Bonn, Bonn, Germany
Leonie C. Storck , Institute of animal science, University of Bonn, Bonn, Germany
Christiane Neuhoff , Institute of animal science, University of Bonn, Bonn, Germany
Luc Frieden , Institute of animal science, University of Bonn, Bonn, Germany
Karl Schellander , Institute of animal science, University of Bonn, Bonn, Germany
Christian Looft , Institute of animal science, University of Bonn, Bonn, Germany
Ernst Tholen , Institute of animal science, University of Bonn, Bonn, Germany
Abstract Text: In total 136 Pietrain boars were mated with crossbred sows from three different breeding companies. 603 boars were performance tested and the concentrations of the boar taint components androstenone, skatole and indole were recorded. To investigate pleiotropic mechanisms affecting these three traits, principal component (PC) techniques were applied to identify common expression pattern. The genome-wide association analyses were performed in the whole data set and in sub- groups according to the line origin. In total, 28 SNPs were significantly associated with at least one of the boar taint components. Only one SNP was identified in both subgroups. The analyses of the phenotypic PCs allowed to identify 12 additional SNPs and to characterize a highly significant region on SSC14 further. Most of the identified regions have been already reported in other studies. The numbers of significant SNPs within the genetic groups show evidence for strong population specific effects.

Keywords:

pig

boar taint

GWAS

pleiotropy