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Genome Wide Association for Heat Stress Tolerance/Susceptibility in Florida Dairy Goats

Monday, August 18, 2014: 5:15 PM
Cypress Room (The Westin Bayshore)
Ali Zidi , Universidad de Córdoba, Córdoba, Spain
Hadeer Abo-Shady , Universidad de Córdoba, Córdoba, Spain
Antonio Molina , Universidad de Córdoba, Córdoba, Spain
Alberto Menéndez-Buxadera , Universidad de Córdoba, Córdoba, Spain
Manuel Sánchez-Rodríguez , Universidad de Córdoba, Córdoba, Spain
Clara J. Díaz , INIA, Madrid, Spain
Maria Jesus Carabaño , INIA, Madrid, Spain
Juan M. Serradilla , Universidad de Córdoba, Córdoba, Spain
Recorded Presentation (flv)
Abstract Text:

Increasing global temperatures might affect negatively the availability of food resources. Therefore, selecting animal adapted to climate change could be a way to guarantee the continuous production of food. With this motivation, genome wide association analysis (GWAS) for susceptibility/tolerance to heat stress was carried out in Spanish Florida dairy goats (n = 538). Several significant SNPs at whole genome level, located in different chromosomes, were identified. Gene annotation and functional classification analysis carried out with BioMart and DAVID online tools showed significant SNP located in genes involved in milk composition such as kappa casein (CSN3), acetyl-coenzyme A carboxylase alpha (ACACA) and malic enzyme 1 (ME1) and a significant SNP (snp39045-scaffold-3419) mapped at the heat shock 27 kDa associated protein 1 (HSPBAP1) which inhibits the antiapoptotic and thermotolerance function of heat shock protein 27 kDa (HSP27) at cell level.

Keywords:

dairy goat

heat stress

genome wide association analysis

See more of: Sheep and Goats Breeding (1)
See more of: Species Breeding: Sheep and goats
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