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GENOME-WIDE ASSOCIATION ANALYSIS OF HARVEST WEIGHT IN A NORTH AMERICAN ATLANTIC SALMON POPULATION

Monday, August 18, 2014: 11:30 AM
Cypress Room (The Westin Bayshore)
J J Tosh , Centre for Genetic Improvement of Livestock, University of Guelph, Guelph, ON, Canada
Ricardo V Ventura , Beef Improvement Opportunities, Guelph, ON, Canada
Keng P Ang , Cooke Aquaculture, Blacks Harbour, NB, Canada
J A K Elliott , Cooke Aquaculture, Blacks Harbour, NB, Canada
Mathew P Kent , Centre for Integrative Genetics, Norwegian University of Life Sciences, Ås, Norway
Sigbjørn Lien , Centre for Integrative Genetics, Norwegian University of Life Sciences, Ås, Norway
Elizabeth G Boulding , Department of Integrative Biology, University of Guelph, Guelph, ON, Canada
Larry R Schaeffer , Centre for Genetic Improvement of Livestock, University of Guelph, Guelph, ON, Canada
Abstract Text: A genome-wide association study (GWAS) of harvest weight was carried out in an aquaculture population of Atlantic salmon. The 478 fish had EBV for this trait and genotypes for 3,318 SNP. The analysis took into account pedigree relationships among individuals to avoid spurious associations due to population structure. False positives arising from the large number of markers tested were controlled through decision thresholds. SNP with P < 0.001 and chromosome-wise false discovery rate < 10% were accepted. This identified 3 SNP on Ssa10 and one on Ssa21, which may be linked to QTL. The data seemed insufficient to warrant proceeding with a validation of the results. Data quantity and quality may have limited detection of the large number of genes suspected to affect harvest weight. More fish with highly accurate EBV is recommended for GWAS of complex traits.

Keywords:

fish

growth

genomics

See more of: Breeding in Aquaculture Species: Salmonids
See more of: Species Breeding: Breeding in aquaculture species
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