Genome Wide Association for growth curve parameters in Brahman cattle

Abstract Text:

The objectives were identify the best model to describe the growth curve in Brahman cattle and characterize single nucleotide polymorphism (SNP) associated with growth curve parameters estimates. Body weights were measured at birth, sixth, twelfth, fifteenth, eighteenth and twenty-fourth months of age. Four nonlinear models were tested and evaluated for goodness of fit. Brody’s model was the most appropriate to describe the growth of Brahman cattle. The genome wide association studies were performed for three growth curve parameters (A, b and K). There were 136 SNPs significantly associated with A spread over all chromosomes. There were found significant SNPs in chromosomes thirteen and twenty five, which has no reports in QTLDatabase. These SNPs can be useful in posterior marker assisted selection and pathway analysis to describe the complexity of growth process in beef cattle.

Keywords:

Beef cattle;

Nonlinear function;

Mature;