This is a draft schedule. Presentation dates, times and locations may be subject to change.
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Administration of Recombinant Bovine Somatotropin Prior to Fixed-Time Artificial Insemination and the Effects on Pregnancy Rates and Conceptus Development in Beef Heifers
Administration of Recombinant Bovine Somatotropin Prior to Fixed-Time Artificial Insemination and the Effects on Pregnancy Rates and Conceptus Development in Beef Heifers
Tuesday, July 11, 2017: 10:00 AM
307 (Baltimore Convention Center)
To determine the effects of recombinant bovine somatotropin (bST; sometribove zinc, Posilac, Elanco Animal Health, Indianapolis, IN) administration at the initiation of a fixed-time artificial insemination (TAI) protocol, on pregnancy rates and conceptus development in replacement beef heifers, 412 Bos taurus beef heifers were enrolled in a complete randomized design at 4 locations from January to July of 2016. All heifers were exposed to the 7-day CO-Synch + CIDR protocol where they received a 100-µg injection of GnRH (Factrel; gonadorelin hydrochloride; Zoetis Animal Health) and a controlled internal drug releasing (EAZI-BREED CIDR; 1.38 g of progesterone; Zoetis Animal Health) insert on d -9, heifers received 25 mg of PGF2α (Lutalyse; dinoprost tromethamine; Zoetis Animal Health) at CIDR removal on d -2, followed by a 100-µg injection of GnRH and TAI 54 ± 2 h later on d 0. Within location, all heifers were randomly assigned to one of two treatments: 1) BST (n = 191); heifers received 650 mg bST on d -9; or 2) CONTROL (n = 223); heifers received no bST on d -9. Blood samples were collected on d -9, -2, 0, 28 and 60 to determine concentrations of IGF-1. Pregnancy was diagnosed via transrectal ultrasonography on d 28 and 60 after TAI by determining the presence of a viable fetus. Conceptus development was assessed by measuring crown to rump length (CRL) on d 28 at the time of pregnancy diagnosis. Concentrations of IGF-1 were similar (P > 0.05) between treatments on d -9, 28, and 60; however, concentrations of IGF-1 were greater (P < 0.001) in bST treated heifers at TAI (372.4 vs 193.7 ng/ml). Pregnancy rates to TAI (PR/AI) were greater (P = 0.028) in CONTROL compared with BST heifers (42.5 vs 29.9%). Overall breeding season pregnancy rates did not differ (P = 0.967) between treatments. No differences (P = 0.668) in CRL (8.8 ± 1.7 mm) were determined on d 28 between CONTROL and BST heifers. Administration of bST at the initiation of a TAI protocol increased IGF-1 concentrations at TAI, failed to increase embryo size, but decreased PR/AI.