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Health and performance comparison of Pyramid 5 plus Presponse SQ versus Bovi-Shield Gold One Shot
Two hundred and sixty-five high risk crossbred steers (251.4 kg ± 3.5) were used in a completely randomized design to compare the efficacy of two multi-valent respiratory virus and bacteria combination vaccines on performance and health. Calves with unknown management and health history were purchased from 4 Missouri livestock auctions. On arrival calves received metaphylaxis, 7-way clostridial vaccine, and were randomly assigned to pen and vaccine treatments, Bovi-Shield Gold One Shot (BSG) (Zoetis Animal Health, Kalamazo, MI) or Pyramid 5 plus Presponse SQ (P5P) (Boeringer-Ingelheim Vetmedica). The objective was to identify differences in performance, health, and/or cost of gain (COG) between vaccine treatments. Calves were offered a ration containing an antimicrobial and coccidiostat for the initial 14 d. On d 14, calves were transitioned to a growing ration and revaccinated with their respective vaccine. Over the 70 d growing period vaccine did not influence treatment rate or mortality (P > 0.05). Initial BRD treatment rates for both treatment groups were 37.3% with 12.3% treated twice, and 3.3% treated three times. Treatment mortality was 5.4% for BSG, and 2.9% for P5P. ADG (1.67 kg/d), DMI (6.78 kg/d), feed efficiency (0.246 kg/kg), and final BW (367.5 kg) were all reduced (P < 0.05) due to morbidity. Healthy calves had greater ADG (1.85 kg/d), DMI (7.25 kg/d), feed efficiency (0.257 kg/kg), and final BW (379.5 kg). A vaccine by morbidity interaction occurred for COG (P < 0.05). Deads out COG was lowest (P < 0.05) for healthy calves and not different (P > 0.05) due to vaccine. Deads out COG for morbid calves was intermediate for BSG and greatest for P5P (P < 0.05). Deads in COG was lowest (P < 0.05) for healthy P5P, intermediate for healthy BSG and greatest (P< 0.05) for morbid calves regardless of vaccine. Vaccine did not influence health or performance.
Keywords: vaccine, morbidity, cost of gain