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Studies of the Genetic Background of a Teat Defect in Pigs Born in Germany and Sweden

Thursday, August 21, 2014: 5:15 PM
Bayshore Grand Ballroom B-C (The Westin Bayshore)
Elisabeth Jonas , Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden
Helena Chalkias , Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden
Christiane Neuhoff , Institute of Animal Sciences, University of Bonn, Bonn, Germany
Gabriella Lindgren , Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden
Dirk-Jan de Koning , Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden
Abstract Text:

To improve the understanding of the genetics underlying the inverted teat defect in pigs, we combined studies from Germany and Sweden. Based on a linkage study in Germany which revealed highly significant loci in an experimental population, confirmation of regions was attempted using commercial animals. A genome-wide association study on commercial pigs was also conducted in Sweden. Since both datasets of commercial pigs had a relatively low number of samples, we tested if microsatellite and data of SNP arrays have, in a combined analysis, enough power to validate loci with a higher reliability.  We combined microsatellite data and haplotypes and verified associated alleles on chromosomes 1, 4, 6, 11, 14 and 18. Approaches like these present an opportunity to re-use old datasets and to increase the power of recent association studies when samples or further funding are not available.

Keywords:

Sow

Inverted teat

Inherited defect

Meta analysis

See more of: Swine Genomics and Difficult Traits
See more of: Species Breeding: Swine
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