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Genome-wide association study for conformation traits and osteochondrosis in pigs

Thursday, August 21, 2014: 5:00 PM
Bayshore Grand Ballroom B-C (The Westin Bayshore)
Eli Grindflek , Norsvin, Hamar, Norway
Hanne Hamland , Norsvin, Hamar, Norway
Torunn Aasmundstad , Norsvin, Hamar, Norway
Abstract Text:

Conformation traits and osteochondrosis are known to be related to robustness, causing animal welfare issues and economic losses in pig production. Conformation traits are thought to have multifactorial background, which involves hereditary predisposition as well as environmental conditions. A genome-wide association study using the Porcine 60K SNPchip was performed to identify chromosomal regions associated with conformation traits and osteochondrosis in pigs. This might contribute to uncover the complex genetic background of these traits and identify positional and biological candidate genes. Total score of osteochondrosis in 8 locations recorded from computed tomography images and eight conformation traits recorded by visual scoring were recorded on altogether 2503 Norsvin Landrace boars. Ten significant (p<0.0005) genomic regions were obtained for five of the traits (front leg knee and pasterns, hind leg pasterns, dipped back and OCT) on SSC’s 2, 5, 6, 7, 8, 13 and 14.  

Keywords:

Genome scan

Conformation traits

Osteochondrosis