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Genomic Regions Affecting Cheese Making Properties Identified in Danish Holsteins

Friday, August 22, 2014: 5:00 PM
Bayshore Grand Ballroom A (The Westin Bayshore)
Vivi R Gregersen , Aarhus University, Molecular Biology and Genetics, Tjele, Denmark
Henriette P Bertelsen , Aarhus University, Molecular Biology and Genetics, Tjele, Denmark
Nina A Poulsen , Aarhus University, Food Science, Tjele, Denmark
Lotte B Larsen , Aarhus University, Food Science, Tjele, Denmark
Frida Gustavsson , Lund University, Food Technology, Engineering and Nutrition, Lund, Sweden
Maria Glantz , Lund University, Food Technology, Engineering and Nutrition, Lund, Sweden
Marie Paulsson , Lund University, Food Technology, Engineering and Nutrition, Lund, Sweden
Albert J Buitenhuis , Aarhus University, Center for Quantitative Genetics and Genomics, Dept. of Molecular Biology and Genetics, Tjele, Denmark
Christian Bendixen , Dept. Molecular Biology and Genetics, Aarhus University, Tjele, Denmark
Abstract Text: The cheese renneting process is affected by a number of factors associated to milk composition and a number of Danish Holsteins has previously been identified to have poor milk coagulation ability. Therefore, the aim of this study was to identify genomic regions affecting the technological properties (rennet coagulation time (RCT) and curd firming rate (CFR)). Markers were genotyped in 373 Holstein cows using the bovine HD beadchip (Illumina Inc.). Two regions were identified for RCT explaining 6.1% and 7.8% of the phenotypic variation, respectively, and five regions were found for CFR explaining between 5.1% and 7.6% of the variation. The regions encompass, among others, the caseins (CN) and CSN3, coding for κ-CN was selected as the candidate gene for a major quantitative trait locus (QTL) on chromosome 6. In addition, CWC15, MAP2K5 and LMAN1 were selected as potential candidate genes.

Keywords:

Milk coagulation

Quantitative trait loci

Dairy cattle

Casein