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Identification of SNP Markers for Resistance to Salmonella and IBDV in Indigenous Ethiopian Chickens

Wednesday, August 20, 2014: 11:30 AM
Cypress Room (The Westin Bayshore)
Androniki Psifidi , The Roslin Institute and R(D)SVS, University of Edinburgh, Midlothian, United Kingdom
Georgios Banos , Scotland's Rural College, Edinburgh, United Kingdom
Oswald Matika , The Roslin Institute and R(D)SVS, University of Edinburgh, Midlothian, United Kingdom
Tadelle Dessie , International Livestock Research Institute, Addis Abeba, Ethiopia
Rob Christley , Institute of Infection & Global Health, University of Liverpool, Liverpool, United Kingdom
Paul Wigley , Institute of Infection & Global Health, University of Liverpool, Liverpool, United Kingdom
Judy Bettridge , Institute of Infection & Global Health, University of Liverpool, Liverpool, United Kingdom
Olivier Hanotte , School of life Sciences, University of Nottingham, Nottingham, United Kingdom
Takele Desta , School of life Sciences, University of Nottingham, Nottingham, United Kingdom
Pete Kaiser , The Roslin Institute and R(D)SVS, University of Edinburgh, Midlothian, United Kingdom
Abstract Text:

Serological data for Salmonella and Infectious Bursal Disease Virus (IBDV) were recorded for 760 indigenous Ethiopian village chickens raised in two distinct geographical regions, Horro and Jarso. Chickens were genotyped with a 620K SNP array. A multidimensional scaling analysis showed that the two populations were genetically distinct. In Horro, genome-wide scans revealed nine SNP with chromosome-wide significant association with Salmonella resistance and seven SNP with genome-wide significant association with IBDV resistance. In Jarso, these scans revealed one SNP with genome-wide and two SNP with chromosome-wide significant association with Salmonella resistance, and one SNP with genome-wide and three SNP with chromosome-wide significant association with IBDV resistance. All significant SNP for each region for either disease were located on different chromosomes. Most of these SNP had a significant additive effect and were located close to annotated genes that are known to impact the immune response in chickens.

Keywords: chickens

               Salmonella

                IBDV

See more of: Poultry Breeding (1)
See more of: Species Breeding: Poultry
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