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SSC4 WUR Genotype and Vaccination Effect on Nursery Pigs Co-infected with PRRSV and PCV2b
Porcine Reproductive and Respiratory Syndrome (PRRS) and Porcine Circovirus type 2b (PCV2b) are detrimental viral diseases to the porcine industry. A total of 206 weaner piglets were randomly assigned to one of two rooms. Pigs in one room were vaccinated for PRRS and 28 days later, all pigs were co-infected with both viruses. The non-vaccinated piglets were 2.06 times more likely to present with blue ear (p<0.05). The effect of vaccination on Average Daily Gain (ADG) varied over time (p<0.0001). The effects of both WUR genotype, a swine chromosome 4 SNP associated with host response to PRRS, and vaccination on PRRS viremia varied significantly over time (p<0.01). Blue ear and mortality after co-infection had a moderate heritable component. The introduction of PCV2b with PRRS may have diluted the impact of the WUR genotype on host response.
Keywords:
Porcine Reproductive and Respiratory Syndrome
Porcine Circovirus type-2b
Host response
