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Analysis of Copy Number Variation Regions in a Nellore Population Evaluated for Feed Efficiency

Monday, August 18, 2014
Posters (The Westin Bayshore)
Gerson A Oliveira Junior , NAP-GMABT/FZEA/University of Sao Paulo, Pirassununga, Brazil
Fernando S B Rey , Sao Paulo State University (UNESP), Jaboticabal, Brazil
Marcos V. G. B. da Silva , Embrapa Dairy Cattle, Juiz de Fora, Brazil
Miguel H A Santana , NAP-GMABT/FZEA/University of Sao Paulo, Pirassununga, Brazil
Pāmela A Alexandre , NAP-GMABT/FZEA/University of Sao Paulo, Pirassununga, Brazil
Joanir P Eler , NAP-GMABT/FZEA/University of Sao Paulo, Pirassununga, Brazil
Jose B S Ferraz , NAP-GMABT/FZEA/University of Sao Paulo, Pirassununga, Brazil
Abstract Text: The systematic study of Nellore’s genome can contribute in a unique way to the development of traits of interest, like feed efficiency. The aims of this study were to identify copy number variation (CNV) and CNV regions (CNVR) in a Nellore population and try to correlate these with feed efficiency genes. Genotype data of the Nellore bulls were recorded, in total 2,457 animals, being 640 phenotyped for residual feed intake. For CNV identification was used the PennCNV software and the CNVRs were determined by the CNVRuler software. A total of 117,175 CNVs were found with approximately 90% between 3 Kb and 1 Mbp. Also, 6,933 CNVRs were detected with average more ‘loss’ than ‘gain’ regions. In summary, the residual feed intake genes analyzed were close or within the genes, suggesting that these CNVRs might have some influence on this trait.

Keywords:  Beef cattle, Genomic, Residual feed intake, SNP

See more of: Posters: Beef Cattle Breeding (Group 2)
See more of: Species Breeding: Beef cattle
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