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Genome-wide Analysis of Genetic Diversity in Autochthonous Spanish Populations of Beef Cattle
Genome-wide Analysis of Genetic Diversity in Autochthonous Spanish Populations of Beef Cattle
Friday, August 22, 2014: 11:15 AM
Bayshore Grand Ballroom D (The Westin Bayshore)
Abstract Text: The BovineHD 770K BeadChip was used on 116 sire/dam/offspring triplets from five Spanish local beef cattle breeds (Asturiana de los Valles, Avileña-Negra Ibérica, Bruna dels Pirineus, Pirenaica and Retinta). The parents were chosen to be as unrelated as possible. We calculated the molecular coancestry for every pair of individuals (within and between populations). From them, Reynolds, Nei’s minimum and standard distances and average FST were calculated for each subset of markers at every Mb along the autosomal chromosomes. The results of the total genetic diversity showed an average FST value of 0.049 (0.015). However, the FST vary enormously across genomic regions, showing remarkable differences with respect to the average estimate. In particular, regions of the chromosomes 2, 5, 6, 11, 13 and 18 showed a global FST greater than 0.15. In these regions a total of 77 genes were identified.
Keywords:
beef cattle
molecular coancestry
genetic diversity