753
Estimation of Linkage Disequilibrium, Persistence of Phase and Effective Population Size of Brazilian Hereford and Braford Breeds

Monday, August 18, 2014
Posters (The Westin Bayshore)
Patricia Biegelmeyer , Federal University of Pelotas, Pelotas, Brazil
Mauricio M Oliveira , Coordination for the Improvement of Higher Level Personnel (CAPES/PNPD), Brasilia, Brazil
Leandro Lunardini Cardoso , Coordination for the Improvement of Higher Level Personnel (CAPES/PNPD), Brasilia, Brazil
Claudia G Gomes , Embrapa Southern Region Animal Husbandry, Bage, Brazil
Roberto H Higa , Embrapa Informática Agropecuária, Campinas, Brazil
Nelson L Dionello , Federal University of Pelotas, Pelotas, Brazil
Alexandre R Caetano , Embrapa Genetic Resources and Biotecnology, Brasilia, Brazil
Juan P. Steibel , Michigan State University, East Lansing, MI
Fernando F Cardoso , Embrapa Southern Region Animal Husbandry, Bage, Brazil
Abstract Text: A set of 41,241 SNP genotypes from 2,435 Hereford (HH) and Braford (BO) bovines were analyzed to estimate linkage disequilibrium (LD) levels, persistence of phase and effective population size of these populations. LD levels were estimated using the squared correlation of alleles at two loci (r2) at varying distances. Average r2 between adjacent SNP was 0.21 for HH and 0.16 for BO. Average inter-marker distance was 61 kb in both breeds. Useful LD values (r2>0.2) were observed at 0-60 kb bins in HH and 0-20 kb bins in BO. Breeds demonstrated moderate to strong persistence of phase at all distances (range=0.53-0.97). The greatest phase correlations (r>0.9) were found in 0-50 kb bins. LD estimates decreased rapidly with increasing distances between SNPs, however, useful LD was observed in genomic regions spanning up to ~50 kb.

Keywords: beef cattle, effective population size, linkage disequilibrium, persistence of phase

See more of: Posters: Beef Cattle Breeding (Group 3)
See more of: Species Breeding: Beef cattle
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