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Genome-Wide Association Study on Long-Yearling Scrotal Circumference in Canchim Cattle

Thursday, August 21, 2014
Posters (The Westin Bayshore)
Marcos E. Buzanskas , Universidade Estadual Paulista Júlio de Mesquita, Faculdade de Ciências Agrárias e Veterinárias, Departamento de Ciências Exatas, Jaboticabal-SP, Brazil
Daniela A Grossi , Centre for Genetic Improvement of Livestock, University of Guelph, Guelph, ON, Canada
Ricardo V Ventura , Centre for Genetic Improvement of Livestock, University of Guelph, Guelph, ON, Canada
Tatiane C S Chud , Univ Estadual Paulista Julio de Mesquita Filho, Jaboticabal, Brazil
Ismael Urbinati , Univ Estadual Paulista Julio de Mesquita Filho, Jaboticabal, Brazil
Sarah Meirelles , Federal University of Lavras, Lavras, Brazil
Fabiana B. Mokry , Universidade Federal de São Carlos, São Carlos, Brazil
Flavio S Schenkel , Centre for Genetic Improvement of Livestock, University of Guelph, Guelph, ON, Canada
Luciana C. A. Regitano , Embrapa Pecuária Sudeste, São Carlos, Brazil
Mauricio Mello de Alencar , Embrapa Southeast Livestock, Sao Carlos, Brazil
Danísio P. Munari , Universidade Estadual Paulista "Júlio de Mesquita Filho", Jaboticabal, Brazil
Abstract Text: Genome-wide association studies provide valuable information for understanding the genetic control of complex traits in livestock. The goal of this study was to investigate the association of the BovineHD BeadChip SNP genotypes with estimated breeding values for long-yearling scrotal circumference adjusted to 420 days (SC420) in Canchim beef cattle. A total 435 SNPs were significantly associated with SC420 (10% chromosome-wise FDR), of which 30 were located in genes on chromosomes 5, 13, and 14, including HEY1, PLCG1, PAG1, ZFHX4, PEX2, FABP5, FABP12, MED30, and TRHR genes. These genes play a role in biological processes related to reproduction, fat deposition, and hormonal systems development. Future studies targeting these regions and genes could provide better understanding of the genetic architecture of reproduction traits in Canchim cattle.

Keywords:

animal breeding

candidate genes

Canchim breed

See more of: Posters: Genetics of Trait Complexes - Reproduction (Group 2)
See more of: Genetics of Trait Complexes: Reproduction
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