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New Insights on the Influence of Leptin Receptor Gene in Bone Traits in Broilers

Thursday, August 21, 2014: 4:30 PM
Cypress Room (The Westin Bayshore)
Adriana M.G. Ibelli , EMBRAPA Swine and Poultry, Concórdia, Brazil
Jane O. Peixoto , EMBRAPA Swine and Poultry, Concórdia, Brazil
Jorge A.P. Marchesi , Universidade do Contestado, Concórdia, Brazil
Luiz L. Coutinho , Universidade de São Paulo/Esalq, Piracicaba, Brazil
Mônica C. Ledur , EMBRAPA Swine and Poultry, Concórdia, Brazil
Abstract Text: It is widely known that leptin receptor gene (LEPR) is related to adipose tissue storage and feed efficiency, being functional expressed in many tissues in chicken. In several species, this gene also plays essential role on growth and ossification. No information on the influence of LEPR in bone differentiation has been shown in chickens. Thus, we aimed to verify the association between bone integrity traits and the LEPR gene. Tibia and femur phenotypic data from 1,412 broilers with 42 days of age were collected.  A SNP on the LEPR chicken gene was genotyped by PCR-RFLP, followed by association analysis using QxPaK software.  Significant associations were found with femur zinc and tibia dry matter contents, tibia breaking strength, tibia weight, and femur length. The A allele was favorable to improve bone quality. This is the first report associating the LEPR with bone integrity in broilers.  

Keywords:

LEPR

chicken

SNP

See more of: Poultry Breeding (2)
See more of: Species Breeding: Poultry
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