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Genome-wide association study for milk total unsaturated fatty acids in Brazilian Holstein cows

Wednesday, August 20, 2014
Posters (The Westin Bayshore)
Juliana Petrini , Department of Animal Science, University of São Paulo/ESALQ, Piracicaba, Brazil
Laiza H. S. Iung , Department of Animal Science, University of São Paulo/ESALQ, Piracicaba, Brazil
Mary Ana P. Rodriguez , Department of Animal Science, University of São Paulo/ESALQ, Piracicaba, Brazil
Fábio Pértille , Department of Animal Science, University of São Paulo/ESALQ, Piracicaba, Brazil
Laerte D. Cassoli , Department of Animal Science, University of São Paulo/ESALQ, Piracicaba, Brazil
Paulo F. Machado , Department of Animal Science, University of São Paulo/ESALQ, Piracicaba, Brazil
Luiz L. Coutinho , Universidade de São Paulo/Esalq, Piracicaba, Brazil
Gerson B Mourao , Department of Animal Science, University of São Paulo/ESALQ, Piracicaba, Brazil
Abstract Text:

The effects of milk fatty acids in human health have encouraged the research of the genetic control under this trait. In this scenario, the objective in this study was to identify the main single nucleotide polymorphisms (SNP) for total unsaturated fatty acids (UFA) content in a Holstein population reared under tropical conditions. Estimated breeding values (EBV) for UFA content were associated to 6,971 SNP for 757 cows using Bayesian LASSO methodology. Of these, two SNP in chromosome 14 were responsible for 4.96 and 4.12% of the additive SNP variance, probably because of their proximity with DGAT1 gene. SNP were also identified in chromosomes 2, 11 and 18. The small effects of the majority of SNP confirmed the polygenic nature of this trait. However, the use of genetic markers can improve genetic selection for milk fatty acids. 

Keywords:

Bayesian Lasso

dairy cattle

milk composition

single nucleotide polymorphism

See more of: Posters: Genetics of Trait Complexes - Lactation
See more of: Genetics of Trait Complexes: Lactation
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