Identification of Genomic Regions Associated with Swine Growth

Thursday, August 21, 2014
Posters (The Westin Bayshore)
Nicholas J Boddicker , Genesus Inc, Oakville, MB, Canada
Pius Mwansa , Genesus Inc, Oakville, MB, Canada
Robert A. Kemp , Genesus Inc, Lethbridge, AB, Canada
Abstract Text: Growth is one of the most economically important traits for commercial swine producers.  The objective of this study was to identify genomic regions associated with growth in Landrace, Yorkshire, and a commercial crossbred population using Duroc sires and Landrace/Yorkshire F1 females. A 4 Mb window on chromosome 1 explained over 11% of the genetic variance for age at 100kg when Landrace and Yorkshire populations were analyzed jointly. In general, the effects of this region, evaluated using 3 different SNPs with high R2values based on window specific genomic estimated breeding values, were significant in all 3 populations and of similar magnitude for age at 100kg and off-test weight. Linkage disequilibrium between these SNPs across populations ranged from 0.27 to 0.93. Melanocortin-4 receptor gene is within the 4 Mb window. The effects of this region in the current populations were similar to those for MC4R.