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Genome wide scan for age at first calving in Gyr dairy cattle

Thursday, August 21, 2014
Posters (The Westin Bayshore)
Adam T. H. Utsunomiya , UNESP Univ Estadual Paulista, Jaboticabal, Brazil
Solomon A. Boison , University of Natural Resources and Life Sciences, Vienna, Austria
Daniel J. A. dos Santos , State University of São Paulo, Faculty of Agriculture and Veterinary Sciences, Jaboticabal, Brazil
Yuri T. Utsunomiya , UNESP Univ Estadual Paulista, Jaboticabal, Brazil
Marco A. Machado , Embrapa Dairy Cattle, Juiz de Fora, Brazil
Rui S. Verneque , Embrapa Dairy Cattle, Juiz de Fora, Brazil
Johann Sölkner , University of Natural Resources and Life Sciences, Vienna, Austria
José F. Garcia , UNESP Univ Estadual Paulista, Araçatuba, Brazil
Ricardo da Fonseca , São Paulo State University “Júlio de Mesquita Filho", Dracena, Brazil
Marcos V. G. B. da Silva , Embrapa Dairy Cattle, Juiz de Fora, Brazil
Abstract Text:

Deregressed estimated breeding values for age at first calving of 1,606 Gyr cows were used in a genome-wide scan using 490,009 SNPs. The 20 largest effects, estimated via the Heteroscedastic Effects Model, were used to prospect positional candidate genes, and CALCRL, PRDM8 , ANTXR2 and FGF5 were investigated in depth as they flank the two SNPs explaining the largest proportions of additive genetic variance across all markers. Most of these genes have important roles on the development of primordial germ cells and reproductive organs. This study contributes to the identification of loci affecting age at first calving in Gyr cattle, and the positional and functional candidate genes reported represent a starting point to the dissection of the molecular biology underlying the trait.

Keywords:

GWAS

Age at first calving

Bos indicus

See more of: Posters: Genetics of Trait Complexes - Reproduction (Group 2)
See more of: Genetics of Trait Complexes: Reproduction
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