Hematological and Biochemical Parameters of Saanen Goats Supplemented with Selenium and Vitamin E during the Transition Period

The objective of this study was to evaluate serum and milk selenium (Se) and vitamin E (VitE), hematological, and biochemical parameters of Saanen goats that were supplemented with Se and VitE. Fifteen goats that were supplemented starting on the fourth month of pregnancy until 28 days after partum. The experimental design was a complete randomized design with repeated measures, with five replications.The animals were divided into three groups and received the treatments: Control (base diet with 50% forage and 50% concentrate); Se (3.2 mg of Se/Kg DM added to the diet) and Sev (3.2 mg of Se/Kg DM and 1145 IU/day of VitE/kg DM). The experiment took 12 weeks. Blood samples were collected before the supplementation, during the partum and 2, 7, 14, 21 and 28 days postpartum. Blood samples were analyzed for Se, VitE, erythrogram, leukogram, serum protein analysis, albumin, gamma-glutamyl transferase (GGT), total cholesterol, high density lipoproteins (HDL), low density lipoproteins (LDL), triglycerides, aspartate aminotransferase (AST), creatine phosphokinase (CK ), glucose, lactate, urea, creatinine, beta-hydroxybutyrate (BHB), non-esterified fatty acids (NEFA) and total antioxidant status (TAS). Milk samples were analyzed for Se and VitE. Time was analyzed when the interaction was significant, except for VitE that was analyzed by analysis of variance and the means were compared by Tukey test (P ≤ 0.05). There was a significant increase in Se concentration in serum and goats’milk (P < 0.05). For VitE in serum and milk, TAS, hematological and biochemical parameters, there was no significant effect of treatment (P > 0.05), Sev treatment tended to improve several parameters such as higher red blood cells, lower cholesterol and HDL, LDL and CK, indicating a better oxidant activity in the group treated with Se and VitE.