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Effects of M. hyopneumoniae vaccination program and water-delivered antibiotic programs on growth performance and morbidity and mortality in wean-to-finish pigs
The objective of this study was to determine the effectiveness of two M. hyopneumoniae vaccination programs and five water-delivered antibiotic programs at improving growth performance, and reducing morbidity and mortality of pigs under commercial conditions during the wean-to-finish period (6.5 ± 0.55 kg to 133.9 ± 1.55 kg BW). A total of 4760 pigs housed in mixed-sex pens (barrows and gilts) of 34 pigs/pen were used. The pigs used came from a population that had a history of M. hyopneumoniae infection. Pigs were kept at commercial floor spaces (0.62 m2/pig) and had ad libitum access to feed and water throughout the study. The study was conducted as a RCBD with a 2 × 5 factorial arrangement of treatments: 1) Mycoplasma Vaccine: Program 1 (2cc RespiSure-ONE® at 3 to 4 d of age and 1cc FosteraTM PCV MH at 28 d post-weaning) vs. Program 2 ( Program 1 + 2cc RespiSure-ONE® at wk10 post-weaning; and 2) Water Antibiotic: Plan 1 (100g/gal Neomycin at weaning for 7 d + 350g/gal OTC and 0.25L/gal Denagard® at d 7 for 7 d) vs. Plan 2 [ Plan 1 + 350g/gal OTC and 0.25L/gal Denagard® (d 28 for 7 d)], vs. Plan 3 [Plan 1 + 40g/gal Aivlosin® (d 28 for 7 d)], vs Plan 4 [ Plan 1 + 350g/gal OTC and 0.25L/gal Denagard® (d 28 for 7 d) + 80g/gal Lincomycin Soluble (wk13 post-wean for 7 d)], vs. Plan 5 [Plan 1 + 40g/gal Aivlosin® (d 28 for 7 d) + 80g/gal Lincomycin Soluble (wk13 post-wean for 7 d)]. There was a Mycoplasma Vaccine by Water Antibiotic treatment interaction (P < 0.05) for overall ADG; however, the differences between treatment subclass means were small and inconsistent. There was no effect (P > 0.05) of Mycoplasma Vaccine or Water Antibiotic treatments on ADFI, G:F, or morbidity and mortality. Fluid testing for M. hyopneumoniae was carried out periodically throughout the study period; positive test results were only observed near the end of the study in pigs subjected to Program 1. These results suggest no differences in performance for the M. hyopneumoniaevaccine programs or the water-delivered antibiotic programs.
Keywords: vaccine, antibiotic, pigs