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The Effects of Group Size and Sub-Therapeutic Antibiotic Alternatives on the Performance of Nursery Piglets: A Model for Feed Additive Evaluation

Tuesday, March 13, 2018: 2:20 PM
212 (CenturyLink Convention Center)
Kristin M. Olsen, Dept. of Animal Science, Iowa State University, Ames, IA
N. K. Gabler, Dept. of Animal Science, Iowa State University, Ames, IA
Chris J. Rademacher, Dept. of Veterinary Diagnostic & Production Animal Medicine, Iowa State University, Ames, IA
Kent J. Schwartz, Dept. of Veterinary Diagnostic & Production Animal Medicine, Iowa State University, Ames, IA
Wesley P. Schweer, Dept. of Animal Science, Iowa State University, Ames, IA
John F. Patience, Dept. of Animal Science, Iowa State University, Ames, IA
The objectives were to develop guidelines for studies evaluating alternatives to sub-therapeutic antibiotic growth promoters (AGP) and to evaluate the effects of AGP alternatives in 2 group sizes on nursery pig performance. A 41-d experiment was conducted in a commercial wean-to-finish barn; 1,300 piglets weaned at 21-d of age (weaned 2 or 4 days prior to experiment; 6.14 ± 0.18 kg BW, PIC 1050 sows and multiple sire lines) were blocked by sire, sex, and wean date, and assigned to 8 treatments: 4 dietary treatments each evaluated across 2 group sizes. The four diet treatments were: negative control (NC), positive control (PC; NC + in-feed antibiotics (chlortetracycline-HCl in phases 1 and 3 and tiamulin hydrogen fumarate in phase 2), zinc oxide with a dietary acid blend (ZA; NC + ZnO + acid), and a bacillus-based direct-fed-microbial combined with resistant potato starch (DR; NC+DFM+RS). The two group sizes were 31 (large pens) or 11(small pens) pigs per pen; floor was modified so area/pig was not different (0.42m2/pig). There were 7 pens/diet with 11 pigs/pen and 8 pens/diet with 31 pigs/pen. Data were analyzed as a randomized complete block design using SAS PROC MIXED with pen as the experimental unit. Pigs naturally experienced acute diarrhea and septicemia in week 1 and PRRSV in weeks 4-6. There was a significant interaction between diet and group size for ADG (P = 0.012); PC compared to NC increased ADG in large and small pens (0.33 vs. 0.26 and 0.33 vs. 0.29 kg/d, respectively; P < 0.05) and ZA increased ADG only in large pens (0.28 vs. 0.26 kg/d; P < 0.05). Small pens had increased ADG compared to large pens when fed NC or DR diets (0. 29 vs 0.26 and 0.28 vs 0.25 kg/d; P < 0.05). Similarly, PC increased ADFI (0.47 vs. 0.40 and 0.47 vs. 0.43 kg/d for large pens and small pens fed PC vs. NC, respectively; P < 0.05). Compared to NC, ZA increased ADFI (0.43 vs. 0.40 kg/d) in large pens only (P < 0.05; diet*group size P = 0.015). Pigs fed PC had greater G:F than NC (0.69 vs. 0.66; P < 0.05), and small pens had greater G:F than large pens (0.67 vs. 0.65; P < 0.05). In conclusion, compared to NC, ZA increased ADG and ADFI in large pens and PC improved performance in both pen sizes. Small pens had increased G:F compared to large pens.